Hotel is located in a residential area of Podil, which is quite nice and quiet, although most of the building are a bit outdated. It's a 2 minute walk from subway "Kontraktova Plosha" - two stops from the historic center (Maydan Nezalezhnosty - The Independence Square, and Hreschatyk - the main Kiev street). You can also take a short walk to the funiculaire that takes you up to the higher part of the town - Andreevsky Spusk - St. Andrew's Descent (a scenic view, highly recommended).
Rooms are small to medium in size, 3* of European standards. All with AC and mini-fridge, a few euro TV-channels to keep up with the news. Free Wi-Fi.
Staff is well-trained - a rare thing in Eastern Europe. Speaks mostly Russian and English. They have some pictures with famous guests on the wall, guys like Pierre Richard and others also stayed here.
For those who wants to be closer to Kiev's nightlife, I would recommend hotels in Hreschatik area (Pushkinska and Gorodetskogo streets, Shevchenko boulevard).
"Pervak" restaurant on the corner of L'va Tolstogo and Shota Rustaveli streets is absolutely recommended to make yourself familiar with traditional ukrainian high-class cuisine. For some light salads, fresh kiwi juices and desserts - visit "Antresol" caffee on Shevchenko boulevard (next to "Lva Tolstogo" subway station) or open terrace restaurants on the adjoining Pushkinska street.

The Domus is about a ten minute walk outside the city centre in a mainly residential area. The facilities are very much as described on the web site. The street is quiet so there is little problem from noise. the rooms are as you would expect from a European four star hotel. Taxis or the metro (if you are brave enough to try and work out the signs!) are very cheap into the city. The metro ride was about 5 pence.

Having looked at some of the very basic and extremely eastern block style hotels in the city centre this was a really good and comfortable choice. Hotel prices in Kiev seem expensive compared to the cost of living for everything else. Many of the staff speak at least some english which is a bonus in this city. The hotel staff arranged for us to be met at the airport by a driver and the cost was the equivalent of about £15. I would say the Domus is a really good bet if you are looking for a comfortable base in Kiev.