Can we get a train from the airport to near the hotel? If so which one? Thanks
There is a bus going from outside the Airport hall at street level. You will find signs for "Bus" inside the arrival hall. It has 'TXL' on the destination window, and it goes direct to the Central Station (Hauptbahnhof). It costs Euro 2.70, and you pay either the driver or in peak periods a seller outside. The hotel Motel One is on the same side of the station, where the bus arrives, you don't have to go through the whole station.
At the airport, take the train to Hauptbahnhof, (main train station) and the hotel is few minutes from there.
Note there are two airports in Berlin. Reviewer m0nika14 is absolutely correct if you land at Tegel airport. There are only two choices at Tegel for transport: bus or taxi. There is no train or underground at Tegel. The other airport is Shonefeld. It's my understanding that you can take a train to Hauptbahnhof from Shonefeld but I have no personal experience with that airport.
Get an answer from Motel One Berlin-Hauptbahnhof staff and past guests.