What tram number goes to your hotel and the name of the stop
Stop Bertramka, tram 9, 10, 16. There are a lot more trams from one stop further - Andel to different directions
We walked from our car hire depot and to the main railway station, and at the time there were works on one of thetram lines. We did use a GPS system; OsmAnd. OsmAnd did lead us up and down a steep hill.
There is information on Prague trams and trains online.
Tripadvisor won't allow me to send the link.
Otherwise ask the hotel staff. They were very helpful.
Get an answer from Central Hotel Tiepolo staff and past guests.