The southern France city of Toulouse is a study in contrasts. Visit the Academie des Jeux Floraux, the oldest literary society in the western world, as well as the Galerie du Chateau d'eau, the world's first photography museum. Stroll the Garonne, before visiting France's most beautiful pipe organ at the Saint-Sernin Basilica. Yet for all its medieval architecture, Toulouse is a modern city, home to the European aerospace industry, as well as bars and restaurants in bustling Place du Capitole.

As host of the first Winter Olympics in 1924, Chamonix will always have a place in the history books. Its main attractions are Mont-Blanc (Western Europe's tallest mountain) and the many ski areas that face the Chamonix Valley. Steep slopes and extreme weather conditions suit advanced skiers best, but there are also runs for beginners. Just make sure everyone in your party knows a green circle from a black diamond. Oh, and another note for the history books—Pierce Brosnan was here (filming a James Bond movie, The World Is Not Enough).

Known for its markets and its striking 19th-century limestone architecture, Kingston is a great base for exploring the Thousand Islands and the St. Lawrence River and its national park. Visit Wolfe Island on the free ferry, or hunt for antiques in nearby villages.