Home to two of America's most prestigious universities, Cambridge exudes a certain intellectual quirkiness. A mix of historical haunts, student hang-outs, alternative art and culture venues, vintage clothing shops, bookstores and ethnic restaurants, the city is, well, really cool. Although it is located just across the Charles River from Boston, Cambridge has a distinct vibe that is noticeable immediately. Start at Harvard Square, a hub of activity and mishmash of trendy stores, outdoor cafes and colorful local characters. Pick up a walking tour map at the visitors information booth in the centre of the Square. The route will take you past many important landmarks including the Mount Auburn Cemetery, Tory Row and the Longfellow National Historic Site. Harvard University offers student-led tours through the illustrious buildings and monuments of its sprawling campus. Art and architecture buffs should meander around the M.I.T campus, which includes outdoor sculptures by masters such as Picasso and 20th-century buildings designed by modern greats like Eero Saarinen and I. M. Pei. Along the way, browse through bookstores, stop to watch street performers and grab a coffee at an outdoor café to take in all this captivating city has to offer.

Cape Ann, just 30 miles from Boston Logan Airport, includes four communities: Gloucester, Rockport, Essex and Manchester-by-the-Sea. The picturesque area that spans the coastline was founded by Pilgrims in 1623 who named it after England's Queen Anne. Today, it's home to fishermen and artists, merchants and writers.

Ogunquit's three-mile stretch of beach is one of the longest in Maine, and also one of the least rocky. The water may never warm up, but it's pristine, and this quaint New England town's attractions make it a perfect, picturesque seaside destination.

El Salvador's capital, San Salvador, is a modern city of wide boulevards and narrow streets, outdoor markets, government buildings, high-rises, monuments, an exuberant nightlife, museums and other cultural institutions. And all set against the backdrop of San Salvador volcano. The city is surrounded by shantytowns as well as affluent suburbs with restaurants and large shopping malls. Peaceful settings such as the botanic garden of Parque Cuscutlan provide a break from the city's hectic pace.

With world-class trails, bouldering in the park and more, Sheffield is known as The Outdoor City — but the adventure doesn’t end when you’ve finished exploring its climbs and rides. With brilliant street food markets, independent microbreweries, a vibrant arts and events scene, and plenty of live music, it has everything travellers need to turn an exhilarating day in the sun into a legendary night out.

Liguria, or the Italian Riviera, boasts a bounty of beaches and resort towns, such as tiny Portofino and stylish Rapallo. Hiking trails lead from Portofino to the villages of Cinque Terre. The Riviera of the Setting Sun runs north from Genoa to the French border. Connected by an extensive rail network, most towns are an easy day trip from one another. Genoa is the region's principal city and is home to the famous Cathedral, the Palazzo Reale and an excellent aquarium.

The charms of the Czech Republic's second-largest city may not be immediate, but spend a few days in this Moravian town and Brno's vibrant, authentic Czech ambiance will win you over. It's a fine way to experience Czech life without the teeming herds of tourists that visit Prague. Art Nouveau, Empire and Neoclassical buildings stand in the bar- and restaurant-packed old city center. Leafy parks abound. Be sure to get a photo with a local landmark, the suspiciously crocodilian Brno Dragon statue.