Home to the University of Binghamton and the birthplace of IBM and the Link Flight Simulator, the city of Binghamton has long been a center of education and industry. The Kopernik Observatory is one of the largest public observatories in the world, running science outreach programs for children of all ages. The Greater Binghamton area also features 9,000 acres of State Forest Land, making it an ideal destination for sports and nature enthusiasts.

Syracuse is a city of hills, valleys, lakes and streams. The city sits on the shore of lakes Onondaga, is within 20 miles of the beautiful Finger Lakes region and 30 miles from Lake Ontario. Syracuse offers big-city amenities with a small-town feel: a symphony orchestra, an opera company, professional sports teams, museums and art galleries. Planning a summer trip? Don't miss the Great New York State Fair at the Empire Expo centre. Planning a winter trip? Bundle up - Syracuse is renowned for its snowy winters

Enveloped by expansive beaches, moss-draped oaks, and salt marshes, Saint Simons Island, part of the Golden Isles chain near Brunswick, is a nearly 18 square mile island, once dominated by rice and cotton plantations. Today, it’s a recreation wonderland with superb championship golf courses, miles of bicycle paths, great fishing, historic sites, and excellent restaurants. If you love golf, you’ll love Saint Simons Island, which is home to the 18-hole King and Prince Golf Course and 27-hole Sea Palms Golf and Tennis Resort. Nearby are 234 more holes of golf at popular spots like the 63-hole Jekyll Island Golf Club and 36-hole Sea Island Golf Club. Anglers have lots of opportunities to fish in the rivers, tidal creeks, sounds and the Atlantic Ocean. You’ll find charters and guides at the Golden Isles Marina, and you can also fish off the St. Simons Island Pier and surf cast on stretches of beach on the island’s north end. For such a compact island, Saint Simons is brimming with historic sites. Don’t miss the Saint Simons Lighthouse, where you can climb the 129 steps for a magnificent view of the island; the Fort Frederica National Monument, which has remnants of the British fort built in the 1700s; and the Bloody Marsh Battle Site, where the Spanish defeated the British in 1742.

Is there any possible way Las Vegas could not be on our "best nightlife" list? The only way we could possibly omit it is on a technicality—since you can do pretty much anything 24/7 in Vegas, it might be wrong to call it "nightlife."

Overlooking the Rhone Valley, Nendaz boasts an incredible panorama of the Alps. As sunny as the French Riviera, Nendaz is perfect for a number of outdoor activities such as skiing (on 400 kilometers of slopes), winter and summer hiking, exploring the area's ancient waterways, or mountain biking. Located at the heart of the largest ski region in Switzerland, Nendaz has plenty of options for beginners and expert skiers alike, with its extraordinary itineraries and extremely varied ski runs.