In Hinduism, Manu was said to have survived a great flood that destroyed the rest of the world. He then recreated mankind in this Kullu Valley town. What a rush, huh? No wonder the towering peaks and verdant terrain of Manali attracts adventure travellers, with heli-skiing, hiking, mountaineering and river rafting the favored active pursuits. Come down from your endorphin high by breathing deeply at the four-story, wooden Hidimba Devi Temple, which sits in the middle of a nearby deciduous forest, or take a medicinal soak in the hot springs burbling from the ground a 30-minute walk from town.

A spot of white in the turquoise waters of the Aegean Sea, the island of Naxos is a unique blend of ancient ruins and beach culture. The largest of the Cycladic Islands, Naxos is the childhood home of none other than Zeus, king of the gods. Upon arrival in Naxos, hike over a causeway to Palatia, where the Portara, a stone gateway to an ancient temple that no longer exists, stands alone, the symbol of the island. At sunset, the views of the island, and the sea beyond, are breathtaking.

If the mention of Mykonos doesn’t immediately bring to mind bright white buildings, turquoise skies and tanned bodies lining golden sandy beaches, you’ve been living under a rock. The most popular Greek Island in the Aegean Sea is all about energy and attracts a diverse and upscale crowd that thrives on its stylish nightlife. During the day some privacy can be had in the more secluded north beaches, but the south beaches are all party. Ski, jet-ski, windsurf, horseback ride, parasail or just save up your energy for the evening ahead, like most of your fellow travellers in Mykonos.

Centrally located Umbria's principal cities include Spoleto, Assisi, and Terni. The capital, Perugia, is famed for its chocolate. Take a tour bus or prepare for daredevil Italian drivers if you opt to rent a car. Assisi's Basilica has a host of treasures, including works by Giotto. The town is also home to the crypt of St. Clare, patron saint of television. St. Francis' meditation retreat is in the mountains to the north. Classes at Velia's Cooking Style in Terni make good use of local produce.

A gorgeous spot that’s a convenient day trip from Milan, Lake Como recently earned fame as home to Hollywood star George Clooney. But celeb-spotting aside, it’s known for jaw-dropping natural beauty, elegant old villas—and the scenic towns surrounding the lake. Check out Varenna, Bellagio, and Menaggio, which offer great views, historic churches, and water-based activities such as ferries and passenger-only boats.

The cultural hub of Malaysia, Kuala Lumpur is visually defined by the iconic Petronas Twin Towers, which, at 88 stories high, are the tallest twin buildings in the world and a vision of modern architecture. On the flip side, the Sri Mahamariamman is the oldest Hindu temple in Malaysia, its façade a colorful totem pole of iconography. Shopping at the Central Market is a joyful experience that involves haggling, handicrafts, and happiness.

Shanghai is the cool, confident face of modern China, and its energy is infectious. Go to the Bund to watch ships on the river and marvel at the huge variety of architectural styles on display, or watch the crowds go by in People’s Square. Shoppers should make a beeline for the Fabric Market, where you can have a suit or dress tailor-made for you at bargain prices. At night, explore all manner of fashionable restaurants, bars and nightclubs or just stroll through the city enjoying the spectacular neon lights.