Welcome to Bluegrass Country, the "Horse Capital of the World". But you don't have to be an avid racehorse fan to enjoy the natural beauty, culture and history that this exciting city has to offer. At the Raven Run Nature Sanctuary, for example, hiking trails wend their way through forests, meadows and gentle creeks, taking you past historic landmarks; there's even a night-time guided walk for admiring the stars. The best place in the world for raising thoroughbred horses, Lexington has over 500 horse farms. The Kentucky Horse Park features films, horse shows and exhibits. Be sure to tour the American Saddle Horse Museum, dedicated to the native Kentucky breed, and watch races at the lovely Keeneland Race Course in season. Historic sites are plentiful here, including the Waveland State Historic Site, the childhood home of Mary Todd Lincoln and the Ashland estate of famed Kentucky statesman Henry Clay.

Hilly Cincinnati boasts a thriving arts scene, major league sports teams, a world-class zoo and aquarium and a revitalized riverfront with shopping, clubs and restaurants. Located on the Ohio River in southwestern Ohio, Cinci claims more than 4,000 restaurants, and more chili restaurants than any other city in the world. Adrenaline-junkies will want to visit the nearby Kentucky Speedway and Paramount's Kings Island, home of the tallest and fastest wooden roller coaster in the world.

Gettysburg is steeped in the history of the Civil War. The epic Battle of Gettysburg, in 1863, resulted in more than 50,000 casualties for the North and South combined. It is also, of course, the place where Abraham Lincoln delivered the immortal Gettysburg Address. The town itself is made up of houses, hotels and taverns dating back several centuries, but Gettysburg offers more modern travel and leisure activities, as well, like wine tastings, orchard tours, shopping and golfing.

Stretching from the fishing village of Puerto Morelos to the biosphere reserve of Sian Ka'an, the Mayan Riviera offers an unforgettable Caribbean coastline experience. Divers and snorkelers will be dazzled by the wrecks of Xcaret and the Puerto Morelos reef. Use a zip line to descend into the sacred subterranean caverns of LabnaHa Eco Park, where you can snorkel an underground river under a canopy of stalactites. The nearby Tulum Monkey Sanctuary will put you in a playful mood.

The landscape that inspired Anne of Green Gables entices legions of lovers to Canada’s smallest province. Peaceful P.E.I. is a slow paced haven, full of distinctively Maritime delights. Red sandstone cliffs rise above gentle beaches. Lonely lighthouses dot rocky bluffs. Deserted trails beckon for romantic roaming.

Known as the Home of Golf, pretty St. Andrews appeals to even those with no interest in the game. Set on a wide bay, the town is dotted with medieval ruins, stately architecture, and—thanks to its large student population—plenty of cozy pubs.