Chiriquí Province is a mountainous wonderland, located near the Barú Volcano. If you’re an adventure and nature lover, you’ll be right at home here, as the region offers everything from white-water rafting and kayaking to zip-line rainforest rides and hiking. More relaxed activities, such as coffee plantation tours and bird-watching, also are available here. To reach Chiriquí, you’ll likely pass through David, Panama’s third-largest city. If you choose to visit the Gulf of Chiriquí, you’ll find first-rate scuba diving, snorkeling, and other water sports that take full advantage of its marine location.

The Outer Banks of North Carolina is a 100-mile stretch of barrier islands dotted with pristine beaches, quaint towns and historic sites. If you love swimming, kayaking, or surfing, be sure to visit the Cape Hatteras National Seashore. To really experience local culture, explore each coastal village and sample as much food as you can along the way. (Pro tip: Try the catch of the day.) If you’re looking for a history lesson, check out Roanoke Island or the Wright Brothers National Memorial. And of course, no day is complete without watching the sunset from Jockey’s Ridge.

The history of St. Louis has been heavily influenced by Westward expansion and blues music. The big "must-see" in this region is the Gateway Arch, while other important sites include the Museum of Westward Expansion, the St. Louis Cathedral and the Anheuser-Busch factory tour. The city offers plenty for the whole family. Children will enjoy the local zoo and the Magic House, while family members will also want to unwind at Forest Park, home to the World's Fair almost a century ago.