Relaxed beaches flank the sunny resort town of Menton, known as "the pearl of France," and its most temperate locale. Nearly a dozen private beaches offer bar service and lounge chairs. The free public beaches are kid-friendly with plenty of aquatic sports to inspire a plunge into the Med.

Getting sick on holiday is a major drag, but if you have to be under the weather, Montpellier is an ideal place to do it. People have studied medicine here for centuries—the Moors established medical schools in the 9th century, and the Université Montpellier’s school of medicine was founded in 1220. Once the local docs give you a clean bill of health, explore the cathedral, mansions and opera house.

Dubai is a destination that mixes modern culture with history, adventure with world-class shopping and entertainment. Catch a show at the Dubai Opera, see downtown from atop the Burj Khalifa and spend an afternoon along Dubai Creek exploring the gold, textile and spice souks. If you’re looking for thrills, you can float above the desert dunes in a hot air balloon, climb aboard a high-speed ride at IMG Worlds of Adventure or skydive over the Palm Jumeirah.

A visit to Pattaya is a wonderful way to explore the beaches along the Gulf of Thailand. Relaxed and family-friendly Jomtien Beach is a hot spot for watersports and seaside massages. The giant Buddha of Wat Khao Phra Bat keeps watch over the city, and the wooden Wang Boran Sanctuary of Truth pays homage to Buddhist and Hindu art and architecture. At night, tons of bars and strip clubs attract an adults-only crowd.