A bustling urban center in quiet New England, Manchester, New Hampshire combines history, industry and business. The Amoskeag Millyard is home to The Millyard Museum, which tracks the history of what is now Manchester back 11,000 years. The Currier Museum of Art focuses on paintings by big names like Picasso and O'Keeffe. Head to the nearby town of Merrimack and visit the Anheuser-Busch Brewery, where guests can taste seasonal beers and see the famous Budweiser Clydesdale horses.

Perfectly positioned at the westernmost tip of sparkling blue Lake Superior, Duluth offers visitors a true escape from the stresses of everyday life and an opportunity to enjoy nature. You can opt for a more leisurely pace: spending time at one of the city's 23 beautiful parks, taking an unhurried drive along the scenic North Shore, bird watching at Hawk Ridge, skipping stones on the Lake with the kids. Or go for a more structured itinerary: the aquarium in the morning, lunch at a sumptuous restaurant on the waterfront plus a tour of the famous Sculpture Walk, then a visit to the historic Railroad Depot in the afternoon. Either way, you are sure to leave Duluth feeling relaxed and refreshed.

Smaller and more intimate than popular resort areas such as San Ignacio and Belize City, the modest capital of Belmopan is nonetheless a vibrant city surrounded by stunning scenery and wildlife. Next to the bustling Market Square, Independence Plaza is home to the prime minister's offices, various pedestrian pathways and the National Assembly Building, designed to resemble a Mayan temple. Outside the city lay the spectacular Guancaste Park as well as the astonishing Hummingbird Highway.

Is there any possible way Las Vegas could not be on our "best nightlife" list? The only way we could possibly omit it is on a technicality—since you can do pretty much anything 24/7 in Vegas, it might be wrong to call it "nightlife."

San Diego embodies laid-back California culture, complete with a Boardwalk, surfing communities, and outstanding Mexican food. Breathe in the fresh ocean air at Sunset Cliffs Natural Park, then gobble down a fresh fish taco at a La Jolla seafood joint. The naval aircrafts at the USS Midway Museum will have you standing at attention. A free Sunday concert at the Spreckels Organ Pavilion is the perfect way to unwind after a Saturday night bar-hop in the thumping Gaslamp Quarter.

Rising up as an indomitable peak at the gateway between Spain and the African coast, Gibraltar is a unique destination with a life that goes beyond its surface. The monolithic Rock of Gibraltar entices tourists with its lush greenery and the friendly Barbary Macaques ubiquitous to the area. Beneath its looming exterior lay the Galleries, a veritable labyrinth of underground passageways running through the Rock. Above ground there is also plentiful tax-free shopping, as well as numerous beaches.