Famed throughout Asia for its heady mix of eastern cultures, Penang Island is Malaysia’s prime melting pot. Roadside vendors serve some of the world’s best street food; its national parks offer white-sand beaches and wildlife; and UNESCO-listed George Town is full of colorful heritage houses.

The cultural hub of Malaysia, Kuala Lumpur is visually defined by the iconic Petronas Twin Towers, which, at 88 stories high, are the tallest twin buildings in the world and a vision of modern architecture. On the flip side, the Sri Mahamariamman is the oldest Hindu temple in Malaysia, its façade a colorful totem pole of iconography. Shopping at the Central Market is a joyful experience that involves haggling, handicrafts, and happiness.

This charming city is a UNESCO world heritage site, with a rich trading history and multicultural heritage. Melaka is a rewarding town to explore and is about two hours from Kuala Lumpur.

Johor Bahru is the second-largest city in Malaysia and, with the opening of two major amusement parks in 2012, it is poised to become a major tourist destination. TripAdvisor travellers also recommend visiting the Arulmigu Sri Rajakaliamman Glass Temple, a unique Hindu temple decorated with brilliant glass mosaics.

The southern Thailand town of Krabi serves as base camp for exploring the province of the same name, a lush region of jungles, limestone cliffs and idyllic isles floating just offshore in the Andaman Sea. Buddhist shrines still used by local monks are tucked into the chambers of the town's top attraction, Tiger Cave. The riverside pier links travellers with ferries and longboats to the best scuba diving, rock climbing and white sand beaches on the coast.

Vietnam's bustling largest city sets the cultural and economic pace for the country. The former Saigon boasts charming French colonial architecture and wide boulevards, usually thronged and choked with traffic. Taxis are an option for seeing the sprawling city. The War Remnants Museum shows the Vietnam War through Vietnamese eyes. Don't miss the impressive Jade Emperor Pagoda. Go to the frenetic Ben Thanh Market for food, flowers or frogs. Tour through the Mekong Delta, past rice paddies and houseboats.

Bangkok is full of exquisitely decorated Buddhist temples—as you go from one to the next you’ll be continually blown away by the craftsmanship and elabourate details. But if you’d rather seek enlightenment in a gourmet meal, or dance the night away, you’ll also enjoy Bangkok—the restaurant and nightclub scenes here are among the best in the world.

The charming Vietnamese capital has aged well, preserving the Old Quarter, monuments and colonial architecture, while making room for modern developments alongside. Hanoi may have shrugged off several former names, including Thang Long, or "ascending dragon", but it hasn't forgotten its past, as sites such as Ho Chi Minh's Mausoleum and Hoa Lo Prison attest. Lakes, parks, shady boulevards and more than 600 temples and pagodas add to the appeal of this city, which is easily explored by taxi.

The village cluster of Ubud is the ideal place to try a famed Balinese massage and soak up the ambiance of one of Asia’s top spa destinations. Acupressure, reflexology, stretching and aromatherapy star in the island's distinctively firm massage treatments. Ubud is also the vivacious centre of Bali’s arts scene, home to a small treasure trove of museums and galleries. Monkey around at nearby nature reserve Monkey Forest Park, home to hundreds of mischievous long-tailed macaques. Don’t miss the valley of tomb cloisters at Gunung Kawi.

Move over, Haussmann and l'Enfant. Beijing's urban planner beat you by a couple of centuries. His name is Kublai Khan. Here, you'll find a wealth of history, both ancient (the Hall of Preserving Harmony, Summer Palace, Forbidden City) and more recent (Chairman Mao Memorial Hall, Tienanmen Square). For the best market experience, choose the Dirt Market over the touristy Silk Market.