The first time you go to New York, go ahead and be a sight-seer—everyone should visit the Statue of Liberty, the Met, Times Square, etc. But on a return trip, pick a neighbourhood and go deep. You’ll find hole-in-the-wall bars, great delis, quirky shops… exploring the non-touristy side of New York is an incredibly rewarding experience for a traveller.

We've heard Toronto described as "New York City run by the Swiss," and it's true—you can find world-class theatre, shopping and restaurants here, but the sidewalks are clean and the people are friendly. The best place to start is literally at the top—the CN Tower, the tallest freestanding structure in the Western Hemisphere.

Welcoming, tolerant Gran Canaria offers a little something for everyone. Families flock to the water parks and beaches of Puerto Rico. Those seeking peaceful escape scamper to Mogan's quiet fishing villages. Gay visitors crowd the bars, restaurants and beaches of Playa del Ingles. Urban attractions are on offer in Las Palmas. Three highways open up the island for those with a rental car or a bus schedule. Prime sites to visit include Iglesia de San Juan Bautista de Arucas and Palmalitos zoo park.

Is there any possible way Las Vegas could not be on our "best nightlife" list? The only way we could possibly omit it is on a technicality—since you can do pretty much anything 24/7 in Vegas, it might be wrong to call it "nightlife."

Everyone who visits Paris for the first time probably has the same punchlist of major attractions to hit: The Louvre, Notre Dame, The Eiffel Tower, etc. Just make sure you leave some time to wander the city’s grand boulevards and eat in as many cafes, bistros and brasseries as possible. And don’t forget the shopping—whether your tastes run to Louis Vuitton or Les Puces (the flea market), you can find it here.

Unassuming Brussels is the capital of Belgium, Flanders and Europe. Medieval Grand-Place is indeed grand, with many 17th-century buildings and daily flower markets. Reopened in 2006, the Atomium, Brussels' Eiffel Tower, provides great views, both inside and out. Architecture fans should visit the Musée Horta, home of Belgian master architect Victor Horta. St Gery's clubs and bars are packed all year round. Seafood eateries abound in Ste Catherine. Exploring the narrow streets on foot is more fun than getting snarled up in traffic.