Families with kids of all ages will love this mountain village, located just two hours from Panama City. Whether you’re up for active sports such as hiking, biking, horseback riding and ziplining through the rainforest—or sightseeing adventures such as the El Nispero Zoo and Serpentario (a snake habitat), you’ll find it here. El Valle de Antón is home to the world’s second-largest extinct volcano—but you’ll still find more modern pleasures here, such as its well-known Sunday Market and elegant spas such as Casa de Lourdes.

Tucked into the Klamath Basin at the southern tip of Upper Klamath Lake, the sunny city of Klamath Falls is in a perfect position to offer cultural excursions and adventurous retreats. Learn about the city's beginnings along the Oregon Trail by riding the quaint Trolley or taking a historic walking tour. Venture to the trails and lakes in the region for cross country skiing, hiking, canoeing or bird watching. Keep an eye out for the bald eagles that make this part of the country their home.

Sink your teeth into the sweet fruit of Medford, Oregon. Known for its delectable pears, the city tempts travelers with this mouth-watering treat. Visit Harry and David's for a factory tour, and maybe a free sample, of one of the country's biggest suppliers of fruit gifts. Tour the area's five covered bridges and take advantage of the mild climate to go hiking, biking or rafting. Or make your way through orchards, creameries and vineyards on a tasty wine and cheese tour.

A coastal town just 20 miles west of Lisbon, Cascais was once a small fishing village, but its idyllic scenery attracted the attention of artists, writers and expelled European nobility in the 20th century. Today, it still attracts high society, but all society comes in force to enjoy the gorgeous beaches and adventure options like sailing and surfing. The Conde de Castro Guimarães Museum, a former palace, is now open to the public and displays an impressive collection of art and artifacts.

Portimao is a sailor’s delight, thanks to its calm waters and beautiful conditions. Plenty of elite international competitions happen here, but you don’t have to be a professional to set sail. Cruising the coast on the double-masted Santa Bernarda pirate ship is a family favorite. On dry land, you can wander the lovely Alvor boardwalk, enjoy a succulent seafood meal or zip around the go-kart track at the Autódromo Internacional do Algarve.