The lively capital of Curacao is a welcoming, upbeat destination with two distinct historic districts divided by the lovely St. Anna Bay. Punda, site of neat, narrow streets, is crammed with shops and museums. Otrobanda, or "The Other Side," is a maze of twisting residential streets, contrasting with the organised grid across the bay. Willemstad's colourful colonial architecture has won its UNESCO Heritage site designation. Diving and swimming with dolphins are popular activities in the bay.

The wineries of Chacras de Coria teem with mysterious old-world charm. Vintages here are distinctive, thanks to the varying altitudes and temperatures of wine country. Take a guided tour of several vineyards to sample the best of what Argentina has to offer. Once you’ve slipped fully into grape haze, retire to a charming B&B or wine-country inn.

The historic quarter of Colonia del Sacramento, founded in 1680, evokes old Lisbon with its Portuguese-influenced architecture and winding streets. The area, located in southwestern Uruguay on the Rio de la Plata, was named a UNESCO World Heritage site in 1995. It's an easy day trip by ferry from Buenos Aires, making the beaches a popular Argentinean escape. Major sights include Iglesia Matriz, the country's oldest church, the Municipal Museum and a 17th-century port jutting into the river.

Puerto Madryn is protected by the Golfo Nuevo, which is formed by Península Valdés and Punta Ninfas, and is one of the most sheltered places on the Patagonian coast. With five kilometers of beaches bordering the city, Puerto Madryn is the gateway to many other attractions in Argentina. Top among them is Valdes Peninsula Nature Reserve, a UNESCO heritage site since 1999.