Lucerne is an ancient town with strikingly modern sensibilities. One of Europe’s oldest covered bridges serves as its centrepiece, and fresco-adorned historic houses line the streets, but it’s also home to the cutting-edge KKL, a concert hall and art gallery. Take the cableways up the Pilatus, Stanserhorn or Rigi mountains for breathtaking views, or see Lake Lucerne on a steamship cruise.

Located on the Rhine River near the borders of France and Germany, Basel contains the country's highest concentration of museums. The culture-centric city, site of the world's most influential art market each June, is also home to the lovely Munster Cathedral, made of red sandstone with a multi-colored tile roof. Green spaces abound, including the popular zoological gardens in the city center. Switzerland's largest site of Roman ruins, Augusta Raurica, are an easy day trip to the east.

Grindelwald is postcard-perfect, a charming example of a Swiss ski resort. There are slopes for all experience levels, plus plenty of snowy activities for those who don’t ski, such as sledding, hiking or snowshoeing. Not feeling particularly active? Just cozy up by crackling fire and enjoy the merry atmosphere. After a long day, nothing’s better than lingering over a pot of Swiss fondue and a glass of crisp wine as you plan the next day’s adventures.

If you’re after a winter sports holiday, you can’t find a more gorgeous place to do it than Interlaken, the popular Swiss resort town. There’s superlative skiing, toboggan rides, miles of sledding tracks (which, like the ski slopes, vary in difficulty), snowboarding… all with amazing views of the mountains. In summer, hike among the ibex at nearby Neiderhorn, or shop for watches in the town’s boutiques.

A powerful force since medieval times, the thriving Swiss capital is an appealing city of museums and collections. Bernmobil is the capital's transport system; a BernCard is valid on its trams and buses. A free bike service is also an option for getting around. The Historical Museum and the Collection of the Bern Museum of Fine Arts house the art and architecture of millennia. The Einstein House and the Paul Klee Centre showcase the work of two of Bern's famous former inhabitants.

This Swiss winter wonderland is also a summer playground. Snow-frosted peaks tower above charming towns and villages like Interlaken. Its position, between lakes Thun and Brienz, makes it a perfect base for cable-car rides up Jungfrau, Mönch and Eiger, or for hikes from the traditional village of Grindelwald. Thun offers exciting summer diving and sailing. To the west, the glitzy resort town of Gstaad attracts Europe's wealthy. The Jungfrau Railway boasts Europe's highest station. The region is accessible by bus or car.

A magnet for skiers and hikers, these dramatic peaks – including the iconic Matterhorn – range from 3,000 to 15,000 feet and spread across three-fifths of the country. Abundant glaciers, scenic valleys and gorgeous alpine lakes add to the region's visual appeal. The Glacier Express train travels the 7.5-hour route through the Swiss Alps from Zermatt to St. Moritz, passing through fairy-tale villages and over 291 bridges along the way.