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Panacea Coffeehouse Cafe & Roastery

66 Commerce St, Waynesville, NC 28786-5738
+1 828-452-6200
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  • Excellent64%
  • Very good28%
  • Average6%
  • Poor1%
  • Terrible1%
Travellers talk about
“panini” (17 reviews)
“sandwiches” (33 reviews)
“lox” (4 reviews)
Closed Now
All hours
American, Cafe, International, Healthy, Vegetarian Friendly, Vegan Options, Gluten Free Options
$$ - $$$
66 Commerce St, Waynesville, NC 28786-5738
All Details
Write a ReviewReviews (221)
Traveller rating
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Time of year

61 - 70 of 221 reviews

Reviewed 25 May 2016 via mobile

I had an iced Carmel latte with their coconut lime cupcake. Cupcake was ok, tasted like a box cake, but it was moist and light. The coffee was rich and flavorful and the scenery was beautiful!

Thank summomnc
Reviewed 10 May 2016

I enjoyed a very nice cappuccino and a light breakfast at this coffeehouse. I also enjoyed the music and the casual atmosphere. I would return.

Thank Laura B
Reviewed 6 May 2016

Happy it's here and while the food price is slightly high it does host tasty combinations. I get it, if you can then you will and folks will pay if they want it. The blandish staff come off as a bit disgruntled and disinterested, I...More

Thank sonda7pod
Reviewed 29 April 2016

This is a wonderful find in the historic district of Waynesville, NC. Located in an old warehouse built circa 1920, Panacea welcomes you with the unmistakable aroma of deep roasted coffee. No, not the aroma of brewed coffee or that of an espresso drink being...More

1  Thank Frederick H
Reviewed 26 April 2016

Dixie ckn sandwich was very good. Came w/ side fruit and chips. 3-B fruit smoothie was really good and so was the iced coffee with caramel. They do have a cold coffee concentrate for us iced coffee lovers. Good atmosphere. Great place to get lunch,...More

1  Thank warfster
Reviewed 27 March 2016 via mobile

We stopped at Panacea when in Waynesville to grab a quick coffee and relax. We were so glad we did. We come up to NC every year and this will be one of our staples! The inside is beautiful and large. Although we just came...More

1  Thank James A
Reviewed 24 March 2016

We received a lunch recommendation from the proprietor of a local pottery shop and headed to Panacea Coffee House and Cafe at 66 Commerce Street in Waynesville. (This is a daytime option only, as the kitchen closes at 4 p.m.) The large warehouse-style space is...More

2  Thank Cynthia M
Reviewed 16 March 2016

Even if you do not like coffee you will enjoy the smell. I am not generally a coffee drinker but I love Panacea. They have great sandwiches and plenty of other drinks to suit your fancy. My favorite is the Iced Chai and Scarlet Begonia...More

1  Thank swoodrow2016
Reviewed 4 January 2016 via mobile

Order the Molly Christo. I have given you all the guidance you will need to enjoy lunch. The sauce that comes with this sammy is amazing. I dip my pretzel sticks in it after the sammy is gone. Eat it!

1  Thank Michael B
Reviewed 3 January 2016

We stopped by this spot yesterday and were so glad we did! The location is great as it is located right on the river. There is an outside space for people to take noisy kiddos and still enjoy their coffee. The inside space is cozy...More

1  Thank Amy V
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Restaurant Details

Rating summary
  • Food
  • Value
Average prices
US$5 - US$12
Breakfast, Lunch, Brunch
Restaurant features
Takeout, Outdoor Seating, Seating, Wheelchair Accessible, Free Wifi
Good for
Kids, Child-friendly, Business meetings
Open Hours
7:00 AM - 5:00 PM
7:00 AM - 5:00 PM
7:00 AM - 5:00 PM
7:00 AM - 5:00 PM
7:00 AM - 5:00 PM
8:00 AM - 5:00 PM
Location and Contact Information
  • Address: 66 Commerce St, Waynesville, NC 28786-5738
  • Location: United States  >  North Carolina (NC)  >  North Carolina Mountains  >  Waynesville
  • Phone Number: +1 828-452-6200
  • E-mail
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