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Rx Restaurant and Bar

421 Castle St, Wilmington, NC 28401-5141
+1 910-399-3080
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  • Excellent69%
  • Very good22%
  • Average7%
  • Poor1%
  • Terrible1%
Travellers talk about
“brunch” (14 reviews)
“pig ears” (17 reviews)
Closed Now
All hours
American, Vegetarian Friendly, Gluten Free Options
$$ - $$$
421 Castle St, Wilmington, NC 28401-5141
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Reviews (205)
Traveller rating
Traveller type
Time of year

1 - 10 of 205 reviews

Reviewed 3 weeks ago

Rx, appropriately named for the pharmacy that originally operated in this building, is one of the best downtown Wilmington, NC, restaurants. Although several blocks outside of the downtown proper, it is still one of the most popular "downtown" choices for informed patrons. The restaurant uses...More

Thank Brentmo
Reviewed 3 weeks ago via mobile

Really good food, friendly staff. Don't be afraid to try the fried pig ears! And best of all, they serve complimentary fresh biscuits with homemade strawberry jam as an option!

Thank Roland K
Reviewed 19 May 2017 via mobile

Knowing it was Mother's Day we knew restaurants would be busy so we had a reservation for this highly rated restaurant. It was going to be our first time at Rx. Walked over from around front street, which in itself was very interesting due to...More

Thank mannart03
Reviewed 7 May 2017

We finally tried Rx last night with friends. The food was fabulous! The fried green tomatoes with pimento cheese and bacon jam were fabulous. I had the pork chop - tender and moist. My husband's shrimp and grits were some of the best he has...More

Thank Sam18Wil
Reviewed 7 May 2017 via mobile

Had a late reservation on a Saturday night for dinner. The restaurant wasn't very crowded and our service was attentive and warm. We started with drink specials which were solid. The heirloom tomato salad was incredible and have since tried to replicate it at home...More

Thank easternNCgirl
Reviewed 14 April 2017

A friend's friend recommended we all meet there for Sunday Brunch. I googled the menu and found some strange sounding menu items. Once there, it was a quaint place with pleasant surprises. Pork belly was bacon, for example. The mini biscuits were excellent! The way...More

Thank Andra' E
Reviewed 12 March 2017 via mobile

We had brunch and the food was really good. My french toast topped with blueberries was wonderful! Great variety of food on the menu - sure to please everyone in your group! Nice atmosphere and good service as well.

Thank TravelerKay
Reviewed 12 March 2017

Our first visit to Rx Restaurant and Bar. It was a weekday evening and the place was pretty busy, even at our 8:00pm reservation time. Friendly and caring staff, they went above and beyond to make our experience the best they could. The wine list...More

1  Thank Roger S
Reviewed 7 March 2017

Make sure to get a reservation. Delicious food, perfectly prepared. Nice size portions. Only negative is the decor

Thank happyWilmington_NC
Reviewed 23 January 2017 via mobile

Recently went here with visiting family members without knowing anything about the restaurant. We were not disappointed. They have a new menu every night, including interesting cocktail options. The night we were there they had five entree options with a variety of ingredients. Nice, comfortable...More

Thank NCTravelfan58
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Questions & AnswersAsk a question
Cynthia F
What is on the brunch menus
18 January 2015|
Response from Betsy V | Reviewed this property |
A wicked good pork belly, grits and egg dish...a twisted Monte Cristo... Eggs Benedict...buscuits and housemade peach jam, lots more...
Cynthia F
How are the oysters
18 January 2015|
Response from Betsy V | Reviewed this property |
Small compared to other varieties/areas I have sampled. But the minionette on the raw ones is inspired....
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Restaurant Details

Rating summary
  • Food
  • Value
Average prices
US$30 - US$30
Lunch, Dinner, Brunch, After-hours
Restaurant features
Reservations, Seating, Waitstaff, Wheelchair Accessible, Serves Alcohol, Full Bar
Dining Style
Casual Elegant
Good for
Child-friendly, Special Occasion Dining, Bar Scene, Local cuisine, Romantic
Open Hours
10:00 - 22:00
17:00 - 22:00
17:00 - 22:00
17:00 - 22:00
17:00 - 22:30
17:00 - 22:30
Location and Contact Information
  • Address: 421 Castle St, Wilmington, NC 28401-5141
  • Location: United States  >  North Carolina (NC)  >  North Carolina Coast  >  Wilmington
  • Phone Number: +1 910-399-3080
  • E-mail
Located in the old Hall's Drugstore on 5th and Castle
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