I have a flight at 11:00 AM out of Malpensa and need transportation from hotel in genoa
There is a direct bus leaving from outside Genoa's Principe train station at 6.07, arriving at Malpensa (T1) at 8.55. By train, you'd have leave at 5.44, arriving at Malpensa at 8.46, with a change in Milan. There is no earlier mode of transport.
Otherwise, you could spend the night in a hotel near Malpensa.
If you're flying direct to the USA, you are normally supposed to be at Malpensa three hours beforehand, so the bus would arrive too late. Go the night before. For trains, enter Genova Piazza Principe to Malpensa Aeroporto T1 on http://www.trenitalia.com/tcom-en